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Protéus Filtre
Microorganisms, Enzymes & Industrial Biocatalysis

Biosolutions by design

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Protéus
Our platform offers innovative technologies and 25+ years of expertise in microbiology, protein engineering and scaling-up biocatalytic processes for sustainable manufacturing & renewable products.
Co-development Partnerships / One-off Services / Proprietary Products
Application Market
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PHARMA APIs SYNTHESIS
SEQENZYM VL API multi-tons biosynthesis on Seqens manufacturing site
  • Enzyme production scale-up from 40L to 300L
  • Biocatalyst loading 0.2%
  • Enzyme cost/kg product is below <5%
  • High specificity ee >99.9%
  • High productivity 200g/L
  • High level of reproducibility
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PHARMA APIs SYNTHESIS
SEQENZYM® AL D-Serine multi-tons biosynthesis on Seqens manufacturing site
  • Enzyme production scale-up from 300L to 15m3
  • High specificity ee >99.9%
  • High substrate concentration >30%
  • Enzyme cost/kg product is below <5%
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FOOD & FEED
SEQENZYM® FT Bioconversion of sucrose into short-chain Fructo-Oligosaccharides (FOS) Benefits of SEQENZYM® FT
  • Independant from sugar source
  • Highest yield > 60% Total FOS
  • Higher purification yields
  • Lowest free Fructose < 1%
  • No color formation < 10 ICUMSA
COSMETICS
Biocatalytic route to Estolides a high naturality process for a plant-based ingredient
  • Biosourced substrates from castor oil (non food crop)
  • Biosynthetic process advantages: Low temperature; No color; Lower energy consumption; No metal catalyst
  • Variable properties: Solid, Liquid, Semi-solid; Emulsion, depends on capping agents; Prolonged release; Well tolerated; GRAS: Oral and topical administration
  • Cosmetic applications: Skin hydration, Natural antioxydant, Hair additive, Texturizing
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FLAVOR & FRAGRANCE
(-)-Ambrox biosynthesis Squalene hopene cyclase optimization
  • 1x round of directed evolution
  • Optimization of the reaction conditions by DoE for the best performing variant
  • Factor 10x productivity improvement
  • Conversion obtained with 125g/L of substrate with the best variant
  >> Click to read the corresponding publication
« Biocatalytic Process for (−)-Ambrox Production Using Squalene Hopene Cyclase ». Source: Advanced Synthesis & Catalysis 360, no 12 (15 juin 2018): 2339‑51
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FLAVOR & FRAGRANCE
Green Notes biosynthesis Optimization of a 13-HPL from guava puree
  • 4x round of directed evolution with homologous enzymes
  • 65,000 variants screened
  • Factor 15x activity improvement
  • Factor 48x thermostability improvement
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AGROSCIENCES
Biocontrol Toxin Discovery Collaborative Project DIETETIC
  • Identification of insecticidal activities against corn rootworm larvae (Diabrotica virgifera virgifera) from Protéus microbial diversity
  • 1’300 strains screened
  • Co-development opportunities
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AGROSCIENCE
SEQENZYM βG Biogas production booster Speeds up time to maximum methanization Increase methanogen potential Characteristics:
  • Fungi cell culture supernatant (liquid form)
  • Cocktail of cellulases & hemicellulases
  • Optimized to degrade cellulosic biomass:
β-glucosidase activity enhanced 240x (on model substrates)
  • Stimulates the breakdown of long-chain, water-swelling polysaccharides (mucilage) into short-chain, water-soluble sugars

SEQENZYM BioHub

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Protéus document center
SEQENZYM-Customized-Kits
SEQENZYM Kit
Discover SEQENZYM Customized Kits for Enzyme hit detection.   >> Click and download the SEQENZYM Customized Kits
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SEQENZYM FT
SEQENZYM FT is a new enzymatic product to convert saccharose into short-chain Fructo-Oligosaccharides (scFOS) >> Click and download the SEQENZYM FT
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SEQENBIOTICS Nutra
  • Explore our microbial collection from exotic ecosystems
  • Expand possibilities within biodiversity with our microbiology services
>> Click and download the SEQENBIOTICS Nutra

Certifications & partnerships

At Protéus by Seqens, we believe in the power of collaboration and continuous learning. As part of our commitment to excellence, we actively engage with scientific associations, industry clusters, and certification bodies.

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